Claire Mérot & team

Research - Evolution, Ecology and Genomics

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Present team

Claire Mérot Researcher - CNRS - claire.merot[a]univ-rennes.fr

I am a researcher at institute ECOBIO, located at University of Rennes (France) where I am leading research about the implication of genome structure in adaptation and the evolution of biological diversity. My group and I are interested in biodiversity, speciation and evolution.

My research integrates ecology, experiments, molecular biology, bioinformatics and genomics to understand evolution. My current projects are largely focused on a fascinating aspects of genetic variation: variation in the structure of the genome.

As a citizen and a scientist, I am concerned by recent changes in biodiversity and impact of humans. Nowadays, protection of biodiversity is a major issue and I believe that involving the whole society in the responsible management of nature requires a better knowledge of living beings. That's why I am taking part in teaching, scientific popularisation and naturalist discovery activities.

Thomas Brazier PostDoc - CNRS - thomas.brazier[a]univ-rennes.fr

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Qiaz Hua PostDoc - CNRS - MSCA fellow - qiaz.hua[a]univ-rennes.fr

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Jana Wold PostDoc - CNRS - MSCA fellow - jana.wold[a]univ-rennes.fr

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Fantine Benoit PhD - CNRS - fantine.benoit[a]univ-rennes.fr

I'm a PhD student at ECOBIO, University of Rennes (2024-2027), in Ecology, Evolution, and Bioinformatics. My research focuses on understanding the impact of structural variants (SVs) on species' local adaptation.

Using a pilot dataset of Coelopa frigida, I optimize bioinformatics methods for detecting SVs, with long reads ( Oxford Nanopore Technologies, PacBio) and linked reads (haplotagging). These methods will then be applied to explore the distribution of SVs across populations along parallel thermal gradients, as well as in experimental populations.

By linking SV, SNPs properties to patterns of genetic diversity and thermal adaptation, my work tries to shed a light on how SVs contribute to local adaptation in natural populations.

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Andrea Clouard PhD - CNRS - andrea.clouard[a]univ-rennes.fr

PhD student at ECOBIO, University of Rennes (2025-2028)

Léa Nicolas PhD - Univ Rennes - lea.nicolas[a]univ-rennes.fr

I'm a PhD student at the University of Rennes, interested in evolutionary ecology, population genetics and population genomics. I'm am passionate about integrating multiple approaches - experimental, genomic, theoretical - to answer complex biological questions.

My research focuses on exploring the role of chromosomal inversions in the adaptive diversity of the seaweed fly Coelopa frigida. Specifically, I investigate whether natural selection is involved in the maintenance of cross-continental parallel clines of an inversion frequency. To address this, I'm experimentally testing the combined effects of the inversion and temperature on key fitness components.

In collaboration with researchers from University of Göteborg, I also use genomics to study the sequence content of two large inversions in Coelopa frigida. Using short-read and long-read sequencing data, I aim to analyze the demographic history of these inversions and to understand to what extent their structure is conserved across continents.

Finally, through a theoretical framework, I will be examining the interplay between the dynamics of these polymorphic supergenes and the evolution of their sequence through the accumulation of deleterious mutations.

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Manon Norest - IE / engineer CNRS - manon.norest[a]univ-rennes.fr

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Dominique Hicks - AI / engineer CNRS - dominique.hicks[a]univ-rennes.fr

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Past members

Dominique Hicks Intern post-master - ENS Lyon (2024-2025) - dominique.hicks[a]univ-rennes.fr

Je suis étudiante en dernière année de l'ENS de Lyon. Depuis la fin de mon master, je m'intéresse à l'évolution des génomes dans un contexte d'adaptation écologique. Cette année j'effectue deux stages avec Claire Mérot (ECOBIO, Rennes) et Maren Wellenreuther (Plant and Food Research, NZ) sur l'évolution d'une inversion ayant un rôle de supergène chez la mouche du varech (genre Coelopidae).

Christine Peré AI/ engineer CNRS

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