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Oὐδὲν χρῆμα μάτην γίνεται ἀλλα πάντα ἐκ λόγου τε καὶ ὑπ᾽ ἀνάγκης

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Creative destruction

Maxwell's demon's genes

 

Shall we be able to reconstruct and synthesize life?
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+  A caveat. The epilogue to The Delphic Boat. Harvard University Press, 2003: Scientists should have no name...

Dealing with information, this site is information-rich; to get a flavour of its content
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An article in english, drawn at random

Origin of life and common sense: how did some believe that arsenic could replace phosphorus?

The classical physical representation of Reality rests on four currencies: space, time, matter and energy. For some time a fifth category, information, begins to be systematically considered as an essential component of this representation. It appears that the discrepancies between classical physics and quantum physics cannot be resolved by assuming the existence of hidden variables, as all the experiments derived from the thought experiments invented by Einstein and others have all refuted their existence. The contradiction is resolved if one introduces information as an essential component of the phenomena of interest. At least from a heuristic point of view, information can be considered as an authentic currency of Reality. Collecting information requires concrete instantiations of Maxwell's demons, combined to creative destruction, a concept that has been revived under a subtle form by Nassim Taleb as antifragility.

Information is central to biology, in a very loose manner in general, essentially via the concept of genetic program and information transfers between the program embodied into nucleic acids and its expression, generally as proteins (which may combine their action to different levels of integration, up to complex behaviours in multicellular organisms for example). In this context of a revolutionary shift of emphasis in the physical sciences, and in the recent developments of biology, we investigate at this site the role of a concept that has often been considered as quite fuzzy, and which is at the centre of many heated controversies, Natural Selection.demon If information is a category of Reality, then accumulation of information over time is a central question to biology. Analysis of the genome of living organisms suggests that specific degradation functions make room by using energy to prevent degradation of what is functional. This process of making room is what we used to name natural selection. It implies that one is able to avoid mixing up reproduction (making a similar copy) and replication (making an identical copy), a separation that has been central to permit the origin of life. As information theories are only fairly recent, it is essential to create new ways to represent this category, and the way it permits exploration and creation of novel components of Reality. We hope that this will be an incentive for young mathematicians to display their inventivity. In parallel, this effort needs to be coupled to experimental approaches in biology, to test the many ways in which living organisms trap information: our quest will be to identify Maxwell's demon's genes...