« This is the blueprint for making a living organism, » I said. I started to provide a more complete explanation, but fell silent. The map spoke for itself. Elegant. Simple. Unfathomably profound.
Beauty bare


Table of Contents
European collaborations
Origin of genome projects

A follow up for microbial databases

When you use the databases please remember that the only way for us to provide continuous support is to show granting agencies that this work is used. Please quote the reference articles in your work.

  • Several updates of the Bacillus subtilis program followed
  • For an update with the methionine salvage pathway please quote:

    E Belda, A Sekowska, F Le Fèvre, A Morgat, D Mornico, C Ouzounis, D Vallenet, C Médigue, A Danchin
    An updated metabolic view of the Bacillus subtilis 168 genome
    Microbiology (2013) 159: 757-770. doi: 10.1099/mic.0.064691-0

    A Sekowska, H Ashida, A Danchin
    Revisiting the methionine salvage pathway and its paralogues
    Microb Biotechnol. (2019) 12: 77-97 doi: 10.1111/1751-7915.13324

    For an update after 20 years please quote:

    R Borriss, A Danchin, CR Harwood, C Médigue, EPC Rocha, A Sekowska, D Vallenet
    Bacillus subtilis, the model Gram-positive bacterium: 20 years of annotation refinement
    Microb Biotechnol. (2018) 11: 3-17 doi: 10.1111/1751-7915.12461

  • Collaboration with the University of Florida and Yale University

    Escherichia coli K12 (MG1655)

  • Please quote:
    C Médigue, A Viari, A Hénaut, A Danchin

    Colibri: a functional data base for the Escherichia coli genome
    Microbiol Rev (1993) 57: 623-654

    C. Médigue, T. Rouxel, P. Vigier, A. Hénaut & A. Danchin
    Evidence for horizontal gene transfer in Escherichia coli speciation
    J Mol Biol (1991) 222: 851-856 pdf

    Please quote:
    E. Duchaud, C. Rusniok, L. Frangeul, C. Buchrieser, A. Givaudan, S. Taourit, S. Bocs, C. Boursaux-Eude, M. Chandler, J-F. Charles, E. Dassa, R. Derose, S. Derzelle, G. Freyssinet, S. Gaudriault, C. Médigue, A. Lanois, K. Powell, P. Siguier , R. Vincent, V. Wingate, M. Zouine, P. Glaser, N. Boemare, A. Danchin & F. Kunst
    The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens.
    Nature Biotechnol (2003) 21: 1307-1313

    and the Beijing Genome Centre (China)

    and Fondaçao de Amparo a Pesquisa do Estado da Sao Paolo (Brasil)

    and also, at the HKU Computer Centre

        Clostridium acetobutylicum


    Collaboration with the Genoscope

    Please quote:
    C Médigue, E Krin, G Pascal, V Barbe, A Bernsel, PN Bertin, F Cheung, S Cruveiller, S D'Amico, A Duilio, G Fang, G Feller, C Ho, S Mangenot, G Marino, J Nilsson, E Parrilli, EPC Rocha, Z Rouy, A Sekowska, ML Tutino, D Vallenet, G von Heijne, A Danchin
    Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125
    Genome Res (2005) 15: 1325-1335  GR biosapiens b7

    and a small eukaryote, the Microsporidion Encephalitozoon cuniculi