Welcome to my personal webpage

I am a CNRS researcher at the Centre Physique Théorique (Université Aix-Marseille, Luminy campus)
and CENTURI (Turing Center for Living Systems) Group Leader.
Please click here for the Out-of-equilibrium Mechanics (OM) team webpage.

Opportunities

Join the OM team! We have post-doctoral openings on the following projects:
- ANR JCJC COVFEFE (COVariant Fluctuating theory of Epithelial Flows): see French/English summaries.
- ANR PRC IMPERIS (Inducing Mechanical Perturbations on the Immune Synapse) with P. Pierobon, E. Donnadieu, J. Fattacioli,
- ANR PRCi CODAC (CO-Dynamics of cell Adhesion and Contraction) with P.-F. Lenne, Ed. Munroe, P. Recouvreux.
- ANR PRC DENDROMORPH (Dendrite Morphology) with T. Lecuit and Claire Bertet.

Please contact me by email for more info. Informal inquiries are welcome.

In addition to joining a dynamic team composed of highly motivated people, please have in mind that the Luminy campus is arguably one the most beautiful campus in the world (see some images here).

Research highlight: Cell motility and Tissue Mechanics

Vertex models
Active nematics in curved geometries
Dendritic arborization

Less recent research

MODCOV-19 initiative

Tissue mechanics
Cell motility
Molecular processes

Publication list

See Google Scholar profile.
  1. Alcanivorax borkumensis Biofilms Enhance Oil Degradation By Interfacial Tubulation
    M. Prasad, N. Obana, S.-Z. Lin, K. Sakai, C. Blanch-Mercader, J. Prost, N. Nomura, J.-F. Rupprecht*, J. Fattaccioli*, A. S. Utada*
    bioRxiv (2022)
  2. Enhanced cell viscosity as a marker of premature senescence induced by lamin A/C alterations
    C. Jebane, A.-A. Varlet, M. Karnat, L. M. Hernandez-Cedillo, A. Lecchi, F. Bedu, C. Desgrouas, Corinne Vigouroux, M.-C. Vantyghem, A. Viallat, J.-F. Rupprecht, E. Helfer, and C. Badens
    bioRxiv (2022)
  3. Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo
    K. Nishizawa, S.-Z. Lin, C. Chardes, J.-F. Rupprecht*, P.-F. Lenne*
    bioRxiv (2022)
  4. Curvature-induced cell rearrangements in biological tissues
    Y. Lou, J.-F. Rupprecht, T. Hiraiwa, T. E. Saunders
    bioRxiv (2022)
  5. Tissue fluidization by cell-shape-controlled active stresses
    S.-Z. Lin, M. Merkel, J.-F. Rupprecht
    arxiv (2022)
  6. Active nematic flows on curved surfaces
    S. Bell (1), S.-Z. Lin(1), J.-F. Rupprecht*, J. Prost*
    Physical Review Letters (2022)
  7. [HAL version]
  8. Mechanical stress driven by rigidity sensing governs epithelial stability
    S. Sonam(1), L. Balasubramaniam(1), S.-Z. Lin(1), ..., J.-F. Rupprecht*, B. Ladoux*
    Nature Physics (2022)
  9. Implementation of cellular bulk stresses in vertex models of biological tissues
    S.-Z. Lin, M. Merkel, J.-F. Rupprecht,
    EPJE (2021) [author pdf]
  10. Screening for SARS-CoV-2 by RT-PCR: Saliva or Nasopharyngeal Swab? Rapid Review and Meta-Analysis
    N. Ibrahimi, A. Delaunay-Moisan, C. Hill, G. Le Teuff, J.-F. Rupprecht, J.-Y. Thuret, D. Chaltiel, M.-C. Potier
    PLOS One (2021)
  11. Group testing as a strategy for COVID-19 epidemiological monitoring and community surveillance
    V. Brault, B. Mallein, J.-F. Rupprecht
    PLOS Computational Biology (2021) + see CNRS press release and interviews in The Academic Times , News Medical, and Biologiste Infos
  12. Cell junction mechanics beyond the bounds of adhesion and tension
    P.F. Lenne, J.-F. Rupprecht, V. Viasnoff
    Developmental Cell (2021) [HAL version]
  13. Deterministic and stochastic rules of branching govern dendritic morphogenesis of sensory neurons
    A. Palavalli, N. Tizón-Escamilla, J.-F. Rupprecht, T. Lecuit
    Current Biology (2020) [HAL version]
    See also our press coverage in La Marseillaise journal.
  14. Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion
    A. P. Le, J.-F. Rupprecht, R.-M. Mège, Y. Toyama, C. T. Lim, B. Ladoux
    Nature Communications (2020) [HAL version]
  15. Embryonic geometry underlies phenotypic variation in decanalized conditions
    A. Huang, J.-F. Rupprecht, and T. E. Saunders
    eLife, 9, e47380 (2020)
  16. Microtubule plus-end dynamics link wound repair to the innate immune response
    C. Taffoni, S. Omi, C. Huber, S. Mailfert, M. Fallet, J.-F. Rupprecht, J. J. Ewbank, N. Pujol,
    eLife (2020)
  17. Shaping the zebrafish myotome by intertissue friction and active stress
    S. Tlili, J. Yin, J.-F. Rupprecht, M. A. Mendieta-Serranoa, G. Weissbart, N. Verma, X. Teng, Y. Toyama, J. Prost, T. E. Saunders
    PNAS 116, 25430 (2019) [HAL version]
  18. Myosin filaments reversibly generate large forces in cells
    J. Lohner (1), J.-F. Rupprecht (1), J. Hu, N. Mandriota, M. Saxena, J. Hone, D. Pitta de Araujo, O. Sahin, J. Prost, M. P. Sheetz
    Nature Physics, 15, 689–695 (2019)
  19. Maximal fluctuations of confined actomyosin gels: dynamics of the cell nucleus
    J.-F. Rupprecht, A. Singh, G. V. Shivashankar, M. Rao, J. Prost
    Physical Review Letters, 120, 098001 (2018) Arxiv version.
  20. Soft inclusion in a confined fluctuating active fluid
    A. Singh, J.-F. Rupprecht, G. V. Shivashankar, J. Prost, M. Rao
    Physical Review E, 97, 032602 (2018) Arxiv version.
  21. Geometric constraints alter cell arrangements within curved epithelial tissues
    J.-F. Rupprecht, K. H. Ong, J. Yin, A. Huang, A. P Singh, S. Zhang, W. Yu, T. E Saunders
    Molecular Biology of the Cell, mbc. E17-01-0060 (2017).
  22. Trade-offs between structural integrity and acquisition time in stochastic super-resolution microscopy techniques
    J.-F. Rupprecht, A. Martinez-Marrades, Z. Zhang, R. Changede, P. Kanchanawong, G. Tessier
    Optics Express, 25, Issue 19, 23146 (2017).
  23. The escape problem for mortal walkers
    D. Grebenkov, J.-F. Rupprecht
    The Journal of Chemical Physics, 146, 084106 (2017) -- Arxiv version.
  24. Perspective: A fresh eye on nonequilibrium systems
    J.-F. Rupprecht, J. Prost
    Science, 352, Issue 6285, p. 514 (2016) , [HAL] .
  25. Optimal search by run-and-tumble particles
    J.-F. Rupprecht, O. Bénichou, R. Voituriez,
    Physical Review E, 94, 012117 (2016) -- Arxiv version.
  26. Velocity condensation of magnetotactic bacteria
    J.-F. Rupprecht, N. Waisbord, C. Ybert, C. Cottin-Bizonne and L. Bocquet
    Physical Review Letter 116, 168101 (2016) --- Arxiv version.
  27. Actin flows mediate a universal coupling between cell speed and persistence
    P. Maiuri (1), J.-F. Rupprecht (1), S. Wieser (1),
    V. Ruprecht, N. Carpi, M. Coppey, S. De Beco, O. Bénichou, N. Gov, C.P. Heisenberg, C. Large-Crespo, F. Lautenschlaeger,
    M. Le Berre, A. M. Lennon-Dumenil, M. Raab, H.R. Thiam, M. Piel, M. Sixt, R. Voituriez,
    Cell, 161, 2, pp 374 (2015).
  28. Exit time distribution in spherically symmetric two dimensional domains
    J.-F. Rupprecht, O. Bénichou, D. S. Grebenkov, R. Voituriez
    Journal of Statistical Physics 158, 1, pp 192 (2015) --- Arxiv version.
  29. Stochastic 3D field mapping using Brownian scatterers
    A. Martinez-Marrades, J.-F. Rupprecht, M. Gross, G. Tessier
    Optics Express, Vol. 22, 23, pp. 29191-29203 (2014)
  30. Kinetics of Active Surface-Mediated Diffusion in Spherically Symmetric Domains
    J.-F. Rupprecht, O. Bénichou, D. S. Grebenkov, R. Voituriez
    Journal of Statistical Physics 147, pp 891 (2012) --- Arxiv version.
  31. Exact Mean Time for surface-mediated diffusion
    J.-F. Rupprecht, O. Bénichou, D. S. Grebenkov, R. Voituriez
    Physical Review E 86, pp 041135 (2012) --- Arxiv version.

Short CV

01/2019 onwards - CNRS researcher at the Centre Physique Théorique (Université Aix-Marseille, Luminy campus).
09/2015 - Research fellow with J. Prost (Mechanobiology Institute, National University of Singapore).
2014-2015 - Post-doctoral research with L. Bocquet (LPS, Ecole Normale Supérieure, Paris).
2012-2014 - Graduate student with R. Voituriez and O. Bénichou (LPTMC, Université Pierre-et-Marie-Curie, Paris).
2008-2012 - Elève at the Ecole Normale Supérieure (Paris).

Administrative duties

2021/2024 - Member of the CoNRS section 02 and 51.

Contact

Email: jean-francois.RUPPRECHT@univ-amu.fr
Address: Centre de Physique Théorique, Université Aix-Marseille, Campus de Luminy, 163 Avenue de Luminy, 13009 Marseille
Office: 5th floor, office 514
Phone: number in my email signature.